At the heart of ChromoDynamics (Lakewood, NJ) flagship product, the HSi-300 Hyperspectral Imaging System is ChromoDynamics' patented acousto-optic tunable filter (AOTF) imaging module. This technology fulfills the promise of multispectral and hyperspectral imaging through unmatched spectral flexibility and switching speed. The performance capabilities of this technology make it ideally suited for high-content, high-throughput fluorescence studies, as well as spectral transmission and reflectance imaging. Potential applications range from live cell and whole animal studies to fixed slide clinical diagnostics.
An AOTF is a high-speed, high-throughput, random-access solid-state optical filter with an adjustable optical passband. ChromoDynamics' proprietary AOTF technology delivers diffraction-limited image quality with variable bandwidth resolution down to 1.5 nm. Wavelength switching time, including computer control overhead, is less than one hundred microseconds.
The ChromoDynamics Hyperspectral Imaging System features an integrated EMCCD scientific camera, AOTF-based spectral filter system, instrument driver and control module and a powerful, intuitive image capture and hyperspectral analysis software suite. A number of fluorescence microscopy research techniques benefit from the speed and resolution of ChromoDynamics hyperspectral imaging technology, such as immunohistochemistry, quantum dots (Q-dots), Fluorescence in-situ hybridization (FISH), Fluorescence resonance energy transfer (FRET), and spectral karyotyping (SKY).