Compiled By barbara goode
High-sensitivity laser scanning microscope
The LSM 780 laser scanning microscope uses new GaAsP detector technology to nearly double imaging sensitivity, compared with previously state-of-the-art systems. It aims to facilitate quick visualization of weakly fluorescent and bleach-sensitive specimens, and perform high-quality imaging of tissues with fine structures. It enables high-speed scanning and provides intelligent enhancement of image dynamics.
Carl Zeiss MicroImaging GmbH, Jena, Germany, bioopticsworld.com/articles/370372</p>
Monolithic laser combiner
The MLC400 monolithic laser combiner system for confocal and fluorescence microscopy includes patented complex monolithic optic (CMO) technology and proprietary fiber coupling capability. The integrated lasers and optics are permanently aligned, offering system stability and ease-of-use. It is compatible with all major microscope systems.
Agilent Technologies, Santa Clara, CA, bioopticsworld.com/articles/371757
Multi-axis stages for super-resolution microscopy
The PI nano1x3 series XY and XYZ nanopositioning stages, designed for inverted microscopes from Leica, Nikon, Olympus, and Zeiss, promise highly accurate motion with sub-nanometer resolution over travel ranges of 200 µm. The low profile (20 mm) design facilitates integration, and a large aperture accommodates such accessories as slide and Petri dish holders.
PI (Physik Instrumente), Auburn, MA, USA, bioopticsworld.com/articles/371425/
Comprehensive gene analysis sets
Solaris qPCR Gene Expression Assays are gene specific pre-designed probe and primer sets for real-time polymerase chain reaction (RT-PCR). The assays are pre-designed using an advanced algorithm and incorporate Minor Groove Binder (MGB) and Superbase technologies for performance and universal cycling. And, they are optimized to assure coverage of all known splice variants of the target gene.
Thermo Scientific, Waltham, MA, USA, bioopticsworld.com/articles/371009
Low-noise green lasers
The Genesis CW green (532 nm) lasers promise low-noise (< 0.1% rms) and excellent mode quality (M2 <1.1). The 1000 S model produces more than 1 watt of output power, while the 500 S delivers more than 0.5 watts. Both are air-cooled, can be directly modulated, and are available in OEM packaging.
Coherent Inc., Santa Clara, CA, bioopticsworld.com/articles/370454
Single-molecule force spectroscopy system
Real-time single-molecule force spectroscopy used to be complicated. But ForceRobot 300's intelligent software automates setup and provides continuous adjustment for efficiency. Integrated optical techniques enable targeted, direct measurement of forces between and within molecules, providing sensitivity sufficient to characterize molecular interactions such as the unfolding of single proteins. It works in stand-alone mode or can be mounted on an inverted optical microscope to enable simultaneous fluorescence microscopy.
JPK Instruments, Berlin, Germany, bioopticsworld.com/articles/370982
Affordable DPSS alternative
Designed for flow cytometry and microscopy applications, the Stradus 488 nm diode laser module provides 50mW output–and thus is an affordable alternative to standard, high-power-output diode-pumped, solid-state (DPSS) lasers.
Vortran Laser Technology Inc., Sacramento, CA, bioopticsworld.com/articles/371443
The Epoch multi-volume spectrophotometer system is designed for monochromator-based absorbance measurements in volumes as low as 2 µL. Together, the microplate spectrophotometer and the software-controlled multi-volume plate target labs with multiple users and multiple assays. With its wavelength range of 200 nm to 999 nm, it provides optimal performance for applications such as nucleic acid and protein quantification.
BioTek, Winooski, VT, bioopticsworld.com/articles/369007