Life Science Techniques

Life science technology--specifically photonics and optics--incorporates techniques such as spectroscopy, for instance, for a range of applications including cytometry and cell sorting, and DNA sequencing and analysis.

Life Science Technique Articles

Nano-FTIR chemically identifies nanoscale sample contaminations, as shown in the AFM images of a polymethylmethacrylate (PMMA) film on a silicon surface

Optical microscopy, spectroscopy duo IDs materials at the nanoscale

07/30/2012

An international team of researchers have developed an optical instrument that can chemically identify materials at the nanometer scale.

Cytometry researchers win awards at CYTO 2012 show

07/27/2012

The International Society for Advancement of Cytometry (ISAC) presented its 2012 awards at the CYTO 2012 show, held June 23–27 in Leipzig, Germany.

Pacific Biosciences, Imec to collaborate on single-molecule sequencing solution

07/25/2012

Genome sequencing technology developer and maker Pacific Biosciences (NASDAQ:PACB) and nanoelectronics research center Imec (Leuven, Belgium) will enter into a multi-year research collaboration focused on developing advanced microchips for highly multiplexed, single-molecule genetic analysis.

SPIE establishes biophotonics technology development award

07/24/2012

SPIE has established a new award—the Biophotonics Technology Innovator award—which will honor extraordinary achievements in biophotonics technology development that show strong promise or potential impact.

A novel microscopy approach—fluorescence correlation spectroscopy coupled with calibrated imaging—revealed the number of Cse4 molecules within single centromeric nucleosomes over the course of the cell cycle

Microscopy method determines how centromere structure forms

07/20/2012

Scientists at the Stowers Institute of Medical Research have developed a microscopy method—pairing fluorescence correlation spectroscopy (FCS) with calibrated imaging—to count the number of fluorescent molecules in a cluster, and then determine how DNA twists into a unique chromosomal structure called the centromere.

Global biophotonics market should exceed $99B by 2018, says GIA

07/18/2012

Global Industry Analysts (GIA) recently released a global report on biophotonics markets, forecasting them to exceed $99 billion by the year 2018.

Optical microscope with the world's fastest camera detects circulating cancer tumor cells

Flow-through optical microscope detects rogue cancer cells

07/11/2012

Knowing that the ability to distinguish and isolate rare cells from a large population of assorted cells is essential for early disease detection and disease monitoring, engineers at the University of California, Los Angeles (UCLA) have developed a new optical microscope that can detect circulating cancer tumor cells, which are precursors to metastasis (the spread of cancer).

SPECTRAL IMAGING/BIOINSTRUMENTATION: Calibrating hyperspectral imaging for biomedical applications

07/01/2012

Normally, a microarrayer—so named because it is capable of laying down hundreds of tiny sample droplets in specific places on a microscope slide's surface—creates DNA arrays for genetic research.

TWO-PHOTON MICROSCOPY/MULTIMODAL IMAGING: Femtosecond laser developments advance two-photon imaging

07/01/2012

Growth in multiphoton microscopy has been driven by advances in laser technology-advances that have also facilitated access to multimodal imaging. For instance, a femtosecond laser that enables multiphoton imaging of multiple features in a specimen simultaneously over a wide range can also enable second-harmonic generation (SHG) and even coherent anti-Stokes Raman scattering (CARS) microscopy.

BIOPHOTONICS INSTRUMENTATION/COMMERCIALIZATION: From bench to business: NIH tech transfer needs industry

07/01/2012

Laser capture microdissection (LCM)-an example of biophotonics technology transferred from National Institutes of Health to industry-has ranked on NIH's top 20 commercial products list for six of the last eight years.

MICROSCOPY/SPECTROSCOPY: AFM-IR: A frontier in nanoscale analysis for biological systems

07/01/2012

You've heard of "lab on a chip" technology. Now say hello to AFM-IR, or "lab on the tip," which combines atomic force microscopy (AFM) and infrared (IR) microspectroscopy to provide both nanoscale resolution and chemical specificity for bioanalysis.

MULTIMODAL IMAGING: Two views at once: Combined imaging boosts biomedical research

07/01/2012

Rather than using a serial approach with different methods of looking at biological events, some platforms provide parallel options.

PRODUCT FOCUS: Spectrometers

07/01/2012

Spectrometers—instruments that measure light intensity or polarization across a specific segment of the electromagnetic spectrum to analyze and identify chemical composition—range in size from tabletop to handheld.

SPECTROSCOPY/NANOTECHNOLOGY: SERS-nanoparticle approach detects ever lower levels of contaminants in water

07/01/2012

SERS and silver nanoparticles are combining forces to boost sensitivity for detection of organic contaminants that occur at low-level concentrations in air and water.

Fluorescence DNA sequencing test for cancer screening wins validation approval

06/26/2012

Acupath Laboratories has received validation approval by the New York State Department of Health for the lab's AcuProbe Spitz test based on fluorescence in situ hybridization (FISH), a technique that detects and localizes the presence or absence of specific DNA sequences on chromosomes.