Life Science Techniques

Life science technology--specifically photonics and optics--incorporates techniques such as spectroscopy, for instance, for a range of applications including cytometry and cell sorting, and DNA sequencing and analysis.

Life Science Technique Articles

FEI’s new MAPS (Modular Automated Processing System) correlative workflow system helps researchers see both large-scale context and small-scale detail in one view

CELL BIOLOGY/IMAGING/ANALYSIS: Cell Bio event highlights and foretells change made possible by biophotonics

01/10/2012

A session on quantitative live cell microscopy by researchers from Harvard Medical School—presented during the American Society for Cell Biology (ASCB) annual meeting (December 3–7, 2011)—demonstrated how computer vision and biology are changing each other.

SPECTROSCOPY/FORENSICS: CSI: Multidimensional Raman spectroscopy

01/01/2012

The ability to analyze body fluid traces is critical for determining the key details of a crime. Now, a combination of advanced statistical methods and multidimensional Raman spectroscopic signatures shows potential for addressing the shortcomings of standard approaches and minimizing false-negatives and positives. What’s more, the approach has several other potential applications.

FEI’s new MAPS (Modular Automated Processing System) correlative workflow system helps researchers see both large-scale context and small-scale detail in one view

CELL BIOLOGY/IMAGING/ANALYSIS: Cell Bio event highlights and foretells change made possible by biophotonics

01/01/2012

A session on quantitative live cell microscopy by researchers from Harvard Medical School—presented during the American Society for Cell Biology (ASCB) annual meeting (December 3–7, 2011)—demonstrated how computer vision and biology are changing each other.

PRODUCT FOCUS: Optics for the life sciences

01/01/2012

Some optics manufacturers cite the life sciences market as being a significant driver of their business.

SPECTROSCOPY/BIOMEDICAL OPTICS: Alfano wins inaugural Britton Chance award

01/01/2012

During BiOS 2011, SPIE announced the launch of the Britton Chance Biomedical Optics award, to honor the memory of the prolific researcher, instructor, and leader whose contributions were so key to biomedical optics and photonics.

SPECTROSCOPY/NANOTECHNOLOGY/POINT-OF-CARE DIAGNOSTICS: Nanotechnology boosts Raman signal in noise-free, ‘lab on a bubble’ approach

01/01/2012

You’ve heard of a lab on a chip: Now a group of researchers have developed a “lab on a bubble” approach to quickly concentrate samples in order to detect biological molecules.

INFRARED ANALYSIS/FLUORESCENCE MICROSCOPY/ONCOLOGY: Grants fund biophotonics device development and application

01/01/2012

For the University of Southampton’s Optoelectronics Research Centre, the new year launches a five-year, £2.6 million ERC Advanced Grant designed to advance biophotonics research in the near- to mid-infrared range that should eventually produce fast, low-cost spectroscopic point-of-care devices and chemical analysis tools for protecting water quality and food safety.

With vibrational molecular interferometry (VMI), the background signal in a single-molecule image vanishes

'Reverse' spectroscopy approach clarifies molecular structure

12/27/2011

Researchers at the University of Twente’s MESA+ Institute for Nanotechnology adopted a "reverse" approach to spectroscopy, which cleans up images by eliminating background noise.

Robert Alfano garners first Britton Chance Biomedical Optics Award

12/20/2011

Robert Alfano, distinguished professor of physics at City College of New York (New York, NY), has been awarded the first SPIE Britton Chance Biomedical Optics Award in recognition of his pioneering work in biomedical optics and ultrafast laser spectroscopy.

A thin, high-contrast grating with subwavelength structure is separated by an air gap from the gain layer of a VCSEL emitting at 1550 nm

PHOTONICS WEST PREVIEW: SPIE Photonics West 2012 continues growth streak

12/07/2011

After outgrowing the San Jose convention center and moving to San Francisco in 2010, SPIE Photonics West 2012 will grow yet again, both in terms of number of attendees as well as technical content and exhibition size.

A combined Raman spectroscopy and OCT probe can screen for skin cancer

Non-invasive RS-OCT instrument screens for skin cancer

12/05/2011

Belfast, Northern Ireland--A joint U.S.-Dutch team is using an Andor near-IR-enhanced Newton camera as part of a Raman Spectroscopy-OCT probe to screen for skin cancer.

In an optical chromatography setup, cells are placed in a flowing fluid (left to right) and remain stationary when the optical force from a laser (right to left) balances the fluid flow

OPTOFLUIDICS: Optical force chromatography performs label-free blood-cell sorting

12/02/2011

The US Naval Research Laboratory (NRL) is aiming to sort particles in biological fluids using laser-based, optofluidic methods that do not require prior knowledge of DNA sequence attributes or attachment of antibodies and/or fluorescent tags.

Abbott, GlaxoSmithKline expand agreement to develop companion diagnostic test

11/29/2011

Abbott Molecular (NYSE: ABT) and GlaxoSmithKline Biologicals S.A. (GSK) are expanding an existing agreement between the two companies to include the development of an additional companion diagnostic test in support of GSK's cancer immunotherapy research program.

Professor James Wilkinson, University of Southampton Optoelectronics Research Centre

U of Southampton's Wilkinson garners major funding for biophotonics program

11/28/2011

Professor James Wilkinson at the University of Southampton’s Optoelectronics Research Centre has been awarded a European Research Council (ERC) Advanced Grant to develop tools for fast, low-cost point-of-care clinical diagnostics and for chemical analysis in water pollution and food safety.