SURGICAL GUIDANCE/ULTRA HIGH-SPEED PROCESSING: The next step in real-time OCT
03/01/2011
To reach its full potential, OCT technology must also be able not just to capture, but also to process and display imagery in real time.
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OPTICAL DETECTION/CELL BIOLOGY: Three approaches succeed in non-fluorescent single-molecule absorption detection
03/01/2011
Optical detection at single-molecule sensitivity, a capability important for molecular biology, was originally accomplished at cryogenic temperatures.
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MICROSCOPY/MACHINE LEARNING: Open-source software automates complex microscopy tasks
03/01/2011
A novel computer program can quickly learn what a scientist is looking for and then automatically perform complex microscopy experiments when it detects corresponding cell features.
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Digital imaging competition brings bug-eyed splendor
03/01/2011
The Olympus BioScapes competition has honored images and movies of human, plant and animal subjects as captured through light microscopes for the past eight years. Entries are judged based on the science they depict, their aest...
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MULTIMODAL IMAGING: OCT reaches further combined with fluorescence, ultrasound
03/01/2011
An interdisciplinary team at the University of Arizona has combined OCT and laser-induced fluorescence (LIF) in a single endoscopy device—and reports higher sensitivity and specificity for distinguishing normal tissue fro...
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Digital imaging competition brings bug-eyed splendor
03/01/2011
The Olympus BioScapes competition has honored images and movies of human, plant and animal subjects as captured through light microscopes for the past eight years. Entries are judged based on the science they depict, their aest...
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MULTIPHOTON MICROSCOPY: Signaling of thousands of neurons imaged at 250 fps in 3-D
03/01/2011
University of California Los Angeles (UCLA) physics professor Katsushi Arisaka thinks that he and his neuroscience colleagues have created the world's fastest two-photon excitation microscope for three-dimensional imaging in-vivo.
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LUNG DISEASE IMAGING: Patents empower first FDA-approved pulmonary imaging system
03/01/2011
In December 2010, the U.S. Food and Drug Administration granted its first 510(k) clearance for optical coherence tomography (OCT)-based imaging for interventional pulmonology.
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LUNG DISEASE IMAGING: Patents empower first FDA-approved pulmonary imaging system
03/01/2011
In December 2010, the U.S. Food and Drug Administration granted its first 510(k) clearance for optical coherence tomography (OCT)-based imaging for interventional pulmonology.
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FLUORESCENCE MICROSCOPY/GENOMICS: Naturally occurring MRNA imaged for the first time
03/01/2011
The work of scientists at Albert Einstein College of Medicine of Yeshiva University, reported in Nature Methods, may eventually help explain the influence of gene expression on human disease: They report successfully visualizin...
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MARKET & TECHNOLOGY STATUS UPDATE: Technology, applications and future directions: OCT in 2011 and beyond
03/01/2011
In 20 years, optical coherence tomography (OCT) has grown from a new invention to a robustly developed technology, and received approval for application in a number of medical markets. How and why has this growth taken place? A...
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FLOW CYTOMETRY/MICROSCOPY: Optical techniques aid lung disease discovery
03/01/2011
Using both flow cytometry and optical microscopy, researchers at Johns Hopkins Children's Center have discovered that a protein involved in cystic fibrosis (CF) also regulates inflammation and cell death in emphysema and may be...
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AWARDS: Fujimoto honored for advances in OCT application
03/01/2011
Citing "advances in the use of optical coherence tomography (OCT)," the Ernst Abbe Fund announced the recipient of the 2011 Carl Zeiss Research Award for outstanding work in international optical research: James G. Fujimoto, Pr...
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LASER TISSUE WELDING/RAMAN SPECTROSCOPY: Light is the only catalyst in this wound-stitching approach
03/01/2011
A number of groups have demonstrated laser tissue welding (LTW)—a technique that aims to make obsolete the practice of stitching wounds with needle and thread.
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SURGICAL GUIDANCE/ULTRA HIGH-SPEED PROCESSING: The next step in real-time OCT
03/01/2011
To reach its full potential, OCT technology must also be able not just to capture, but also to process and display imagery in real time.
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