OPTOGENETICS/NEUROLOGY: Neurophotonics is...the Future of Light!

The full-day 15th annual Future of Light Symposium, held December 1, 2011, at Boston University’s Photonics Center, explored topics in neurophotonics, providing a specific focus on optogenetics and advanced imaging techniques.

The first half of the day was devoted to optogenetics, and a number of researchers addressed it: Ed Boyden of MIT; Adam Cohen of Harvard University; Alan Horsager of the University of Southern California and EoS Neuroscience (a company he co-founded); and John Spudich of the University of Texas Medical School at Houston. Boyden discussed his team’s work in optogenetics, which seeks to facilitate better and less costly drugs for treating brain disorders. Specifically, he described creating a fiber-optic implant by coupling optical fibers to LEDs, and shining its light on neurons linked with channelrhodopsin in mice, which can reveal 3-D neural activity patterns. The work could create targets for treating several brain disorders in humans. In mice the technique has cured certain forms of blindness, and shows potential for cure for post-traumatic stress disorder (PTSD).

Cohen’s work had been published in Nature Methods just three days before: He explained use of a gene from a Dead Sea microorganism to produce a voltage-indicating protein (VIP) that fluoresces at <500 µs when exposed to the electrical signal in a neuron. The approach allowed Cohen and his colleagues to trace the propagation of signals through the neuron. The work shows immediate promise for drug discovery, but holds future promise for genetic disorder diagnosis. —Lee Mather

For more on this and other events—and additional biophotonics topics—follow the BioOptics Worldview Blog at www.bioopticsworld.com/blogs/biooptics-worldview-blog.html.

More BioOptics World Current Issue Articles
More BioOptics World Archives Issue Articles

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

Noninvasive transcranial NIR light therapy has potential to treat PTSD

Findings on the effects of transcranial NIR light therapy could result in an noninvasive treatment for brain disorders like PTSD.

Optogenetics: Ten years after - Optogenetics progresses in clinical trials

RetroSense Therapeutics announced success in its initial clinical trial - the first to involve therapeutic application of optogenetics.

Two-photon microscopy images touch-sensitive sensory receptors in mouse fingertips

Using two-photon microscopy may help to understand the mechanism of mechanoreceptor function.

New bioimaging technique offers clear view of nervous system

Scientists at Ludwig-Maximilians University have developed a technique for turning the body of a deceased rodent entirely transparent, revealing the central nervous system in unprecedented clarity....

Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...



Twitter- BioOptics World

Copyright © 2007-2016. PennWell Corporation, Tulsa, OK. All Rights Reserved.PRIVACY POLICY | TERMS AND CONDITIONS