LIGHT MICROSCOPY/CELL BIOLOGY: Optical slide innovation enables bacterial motility discovery

An innovation in optical microscopy substrate has enabled a discovery that overturns scientific assumption and provides insight into the way bacteria move.1 The contrast-enhancing slides, called Surfs by French developer Nanolane, were designed to enhance nanometric characterization with a conventional inverted light microscope to <1 nm resolution, and to facilitate the study of biological samples, biofilms, and organic layers in liquid or in air.

Scientific literature has purported that bacteria move using slime that is produced at one end of the organism. But researchers with INSERM and CNRS at Aix-Marseilles University (France) have demonstrated that slime is generated along the entire length of the organism, and that this material helps a bacterium both propel itself across a surface and adhere to the surface.

The researchers used Surfs to complement their wet-surface enhanced ellipsometric contrast (SEEC) microscopy technique. They hope that their discovery enables better understanding of the roles of bacteria and extracellular matrices in such fields as cancer biology and bacteriology. Surfs are compatible with most nano-analytical methods and instruments, including microfluidics, fluorescence, and atomic force microscopy.

1. Ducret et al., PNAS, doi:10.1073/pnas.1120979109 (2012).

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

New bioimaging technique offers clear view of nervous system

Scientists at Ludwig-Maximilians University have developed a technique for turning the body of a deceased rodent entirely transparent, revealing the central nervous system in unprecedented clarity....

Fluorescent jellyfish proteins light up unconventional laser

Safer lasers to map your cells could soon be in the offing -- all thanks to the humble jellyfish. Conventional lasers, like the pointer you might use to entertain your cat, produce light by emittin...

Fluorescence microscopy helps provide new insight into how cancer cells metastasize

By using fluorescence microscopy, scientists have discovered an alternate theory on how some cancer cells metastasize.

In vivo imaging method visualizes bone-resorbing cell function in real time

In vivo imaging can visualize sites where osteoclasts (bone-resorbing cells) were in the process of resorbing bone.


Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...



Twitter- BioOptics World

Copyright © 2007-2016. PennWell Corporation, Tulsa, OK. All Rights Reserved.PRIVACY POLICY | TERMS AND CONDITIONS