Laser Doppler technique detects skin cancer noninvasively

Researchers at Lancaster University (England) and Pisa University (Italy) have developed a noninvasive technique that can accurately detect skin cancer without a biopsy. The technique uses a laser Doppler system to detect the subtle differences in blood flow beneath the skin, which enabled the researchers to tell the difference between malignant melanoma and noncancerous moles.

During the study, 55 patients with atypical moles agreed to have their skin monitored by researchers at Pisa University Hospital using the laser Doppler system. The laser Doppler was used to record the complex interactions taking place in the minute blood vessels beneath their suspicious mole for around 30 minutes. The fluctuations in recorded signals were then analyzed using methods developed by physicists at Lancaster University.

The patients in the study then went on to have their moles biopsied and the results were compared with the information obtained—noninvasively—using the laser Doppler scan. The laser Doppler signal correctly identified 100% of the patients with malignant skin, with 100% sensitivity and 90.9% specificity.

Full details of the work appear in the journal Scientific Reports; for more information, please visit http://dx.doi.org/10.1038/srep12825.

Follow us on Twitter, 'like' us on Facebook, connect with us on Google+, and join our group on LinkedIn

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

Raman scattering method can detect pluripotent stem cells with high sensitivity

An extremely sensitive technique for detecting pluripotent stem cells is at the scale needed for clinical applications.

Method that speeds disease detection has potential for use with portable optical readers

A new method to speed and simplify detection of proteins in blood and plasma is promising for use with portable optical readers.

FDA authorizes emergency use of Zika virus molecular detection assay

The xMAP MultiFLEX Zika RNA assay combines optofluidics and digital signal processing to detect Zika virus in vitro.

'Lab on a stick' test optically and rapidly detects antibiotic resistance

A point-of-care test, based on the dipstick method, can rapidly detect bacterial resistance to antibiotics in urine.

BLOGS

Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...

CONNECT WITH US

            

Twitter- BioOptics World

Copyright © 2007-2016. PennWell Corporation, Tulsa, OK. All Rights Reserved.PRIVACY POLICY | TERMS AND CONDITIONS