Impedance spectroscopy helps test for blood sugar noninvasively

Recognizing that current methods for diabetes patients to measure their blood sugar are painful and inconvenient, an international team of researchers from RWTH Aachen University in Germany, Delft University of Technology (The Netherlands), and the Indian Institute of Technology (Delhi, India) have—using a spectroscopic technique—developed what they call an entirely noninvasive blood sugar test.

Related: Novel design helps photoacoustic spectroscopy clear hurdles to noninvasive glucose measurement

Related: Light-sensitive genetic switch promises injectionless insulin therapy

To measure blood glucose concentrations, diabetes patients typically have to prick a finger to obtain a blood sample and then use a glucose monitor to determine whether or not to take insulin or eat something sugary. So, the research team turned to impedance spectroscopy to help develop a system for patients to determine blood glucose concentrations without having to obtain a blood sample.

The spectral lines obtained by impedance spectroscopy depend crucially on the concentration of glucose in a blood sample. First, the researchers used a standard solution in vitro that contained different concentrations of glucose. Then, they placed electrodes on the forearm of a volunteer and recorded the impedance spectrum through the skin without needing to pierce it. The reference then revealed the blood glucose concentration noninvasively.

However, with their prototype, there are several other factors that can affect such impedance spectra, including patient-to-patient variation in skin type and skin moisture as well as related factors that would affect readings day to day for the same patient. The team is investigating these issues, and intends to take their prototype to the next stage in research and development.

Full details of the work appear in the International Journal of Biomedical Engineering and Technology; for more information, please visit http://dx.doi.org/10.1504/IJBET.2014.059672.

-----

Follow us on Twitter, 'like' us on Facebook, and join our group on LinkedIn

Subscribe now to BioOptics World magazine; it's free!

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

Optical sensor could assist with needle placement for epidurals, other procedures

A newly developed optical sensor can be embedded into an epidural needle, helping to guide the needle to the correct location.  

Spectroscopy: Raman spectroscopy advances for biomedical applications

Raman spectroscopy offers unique analytical capabilities applicable to a wide array of life science applications.

Multispectral method is noninvasive for imaging tissue oxygenation

A new multispectral approach for imaging tissue oxygenation could eliminate the need for surgical intervention.

Raman spectroscopy can help study blood stored in plastic blood bags

Raman spectroscopy can help study blood stored in plastic blood bags

Raman spectroscopy can monitor biochemical changes and inter-donor variability in stored red blood cell units.

BLOGS

Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...

CONNECT WITH US

            

Twitter- BioOptics World

Copyright © 2007-2016. PennWell Corporation, Tulsa, OK. All Rights Reserved.PRIVACY POLICY | TERMS AND CONDITIONS