Clinical trial for multibeam OCT system yields positive top line results

Michelson Diagnostics (Orpington, England) recently completed a multicenter, prospective clinical trial for basal cell carcinoma diagnosis using the company's VivoSight multibeam optical coherence tomography (OCT) system, with positive top line results.

Related: Michelson Diagnostics finalizes data collection in OCT trial for basal cell carcinoma diagnosis

In the study, over 250 patients with clinically suspicious lesions for basal cell carcinoma were scanned at six centers in Germany. In each case, diagnosis using VivoSight was compared with standard clinical diagnosis with and without dermoscopy. All results were verified by biopsy and histological analysis, which is the current gold standard.
Papers by Professor Dr. med. Julia Welzel and Dr. med. Martina Ulrich discussing the results from the clinical study were presented at the American Academy of Dermatology’s 72nd Annual Meeting (AAD) in Denver, CO, on March 25, 2014.
"VivoSight enabled a statistically significant improvement in the specificity and negative predictive value (NPV) of basal cell carcinoma diagnosis over both clinical and dermoscopy on this cohort of challenging pink patches," as concluded by Ulrich in her AAD presentation. She added that because the system treats patients noninvasively, it therefore renders many biopsies unnecessary.
Full results will be published in a peer-reviewed journal later in 2014.


Follow us on Twitter, 'like' us on Facebook, and join our group on LinkedIn

Subscribe now to BioOptics World magazine; it's free!

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

Eye test that pairs two in vivo imaging methods may detect Parkinson's earlier

A low-cost, noninvasive eye test pairs two in vivo imaging methods to help detect Parkinson's before clinical symptoms appear.

Lightweight handheld probe for OCT provides insight into children's retinas

A handheld device is capable of capturing OCT images of a retina with cellular resolution in infants and toddlers.

Optical brain imaging noninvasively measures small perfusion changes caused by visual stimulation

An optical brain imaging system can track very small, focal changes in cortical perfusion resulting from visual stimulation.

Optical Coherence Tomography: Beyond better clinical care: OCT's economic impact

The optical coherence tomography (OCT) industry has grown dramatically in its first 25 years.


Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...



Twitter- BioOptics World