LED Medical Diagnostics, BC Cancer Agency, and Genome BC sign agreement to develop oral cancer test

LED Medical Diagnostics (Burnaby, BC, Canada) has signed an agreement with the BC Cancer Agency and, in turn, Genome British Columbia (Genome BC) to create and commercialize a progression-risk assessment test for oral cancer. The test, the first of its kind for oral cancer, is based on a quantifiable genetic phenomenon known as loss of heterozygosity (LOH).

Related: Study supports tissue fluorescence visualization technology for oral cancer detection

The technology, which performs tissue fluorescence visualization, could help clinicians distinguish between high- and low-risk oral precancers, explains Peter Whitehead, LED Medical Diagnostics'  founder and director. "Until recently, a major barrier to oral cancer prevention has been the lack of validated risk predictors for oral premalignant lesions," he adds.  "In other words, there has been no way, until now, to know whether or not an oral lesion is likely to convert into cancer. This test, which measures specific genetic changes that have been shown to predict aggressive tumour growth, has the potential to lower oral cancer morbidity and mortality rates."

Oral cancer's reputation as a killer is based on statistical reality: the disease is commonly detected late, when the necessary interventions are profound, and the prognosis pessimistic. "Throughout the development process," says Whitehead, "we will strive to create the first test that quantifies the likelihood that an oral lesion will progress to cancer. Its modality as a minimally invasive, in-office procedure potentially means that high-risk lesions can be diagnosed earlier. The clinician, in turn, can fast-track patients who test positive for LOH onto the appropriate disease-management pathway, which will mean less invasive, less costly treatments, and more optimistic long-term prognoses. On the other hand, patients with lesions that test negative for LOH can be spared the psychological and physical trauma of unnecessary and costly interventions."

The project, titled "Development of an actionable molecular test for risk assessment of oral precancers," is funded by the Genome BC Strategic Opportunities Fund, and is designed to leverage research funded by the National Institute of Health and the Terry Fox Research Institute.


Follow us on Twitter, 'like' us on Facebook, and join our group on LinkedIn

Subscribe now to BioOptics World magazine; it's free!

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

New bioimaging technique offers clear view of nervous system

Scientists at Ludwig-Maximilians University have developed a technique for turning the body of a deceased rodent entirely transparent, revealing the central nervous system in unprecedented clarity....

Fluorescent jellyfish proteins light up unconventional laser

Safer lasers to map your cells could soon be in the offing -- all thanks to the humble jellyfish. Conventional lasers, like the pointer you might use to entertain your cat, produce light by emittin...

Fluorescence microscopy helps provide new insight into how cancer cells metastasize

By using fluorescence microscopy, scientists have discovered an alternate theory on how some cancer cells metastasize.

In vivo imaging method visualizes bone-resorbing cell function in real time

In vivo imaging can visualize sites where osteoclasts (bone-resorbing cells) were in the process of resorbing bone.


Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...



Twitter- BioOptics World

Copyright © 2007-2016. PennWell Corporation, Tulsa, OK. All Rights Reserved.PRIVACY POLICY | TERMS AND CONDITIONS