Photoacoustic spectroscopy can measure blood sugar noninvasively

A team of researchers from the Biophysics Institute at the University of Frankfurt in Germany has devised a novel, noninvasive spectroscopy-based approach to make blood glucose monitoring in diabetes easier. Using infrared (IR) laser light applied on top of the skin, they can measure sugar levels in the fluid in and under skin cells to read blood sugar levels.

Related: Noninvasive blood glucose measurement clears hurdle

The work could lead to a cheaper means for patients to measure their blood glucose levels without pricking and test strips, explains lead researcher Werner Mäntele, Ph.D. The optical approach uses photoacoustic spectroscopy (PAS) to measure glucose by its mid-IR absorption of light. A painless pulse of laser light applied externally to the skin is absorbed by glucose molecules and creates a measurable sound signature that enables researchers to detect glucose in skin fluids in seconds.

Related: Photoacoustic tomography is ready to revolutionize

Related: Photoacoustic device promising for routine breast cancer screening

The data showing the skin cell glucose levels at one-hundredth of a millimeter beneath the skin is related to blood glucose levels, Mäntele says, but previous attempts to use PAS in this manner have been hampered by distortion related to changes of air pressure, temperature, and humidity caused by the contact with living skin.

To overcome these constraints, the team devised a design innovation of an open, windowless cell architecture. While it is still experimental and would have to be tested and approved by regulatory agencies before becoming commercially available, the team continues to refine it.

In a close collaboration with an industry partner (Elte Sensoric; Gelnhausen, Germany), they expect to have a small shoebox-sized device ready in three years, followed by a portable glucometer some years later.

Full details of the work appear in the Review of Scientific Instruments; for more information, please visit http://scitation.aip.org/content/aip/journal/rsi/84/8/10.1063/1.4816723.

-----

Follow us on Twitter, 'like' us on Facebook, and join our group on LinkedIn

Subscribe now to BioOptics World magazine; it's free!

POST A COMMENT

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

Green light reduces light sensitivity, headache severity in migraine sufferers

Exposing migraine sufferers to a narrow band of green light significantly reduces photophobia and can reduce headache severity.

Exposure to bright blue light during meals increases insulin resistance

Bright blue light exposure increased insulin resistance compared to dim light exposure in both the morning and the evening.

MRI-guided laser ablation shows promise for prostate cancer treatment

Focal laser ablation is both feasible and safe in men with intermediate-risk prostate cancer.

Biophotonics: PIX4life targets biophotonics with visible-range PICs, development capacity build

Photonics has become critical to life sciences -- however, the field is far from benefiting fully from photonics' capabilities.

Tiny OCT retinal scanner could diagnose blindness early

A compact, cost-effective retinal scanner that uses OCT imaging to diagnose retinal diseases early is being developed.

Sensor pairing two optical methods shows promise for high-speed disease detection

A highly sensitive sensor that combines two optical methods could enable new high-speed disease detection.

FDA approves at-home laser therapy device to treat male and female hair loss

The FDA has cleared Capillus' low-level laser therapy Capillus caps for treating androgenetic alopecia in both men and women.

Biophotonics-enabled device could eliminate unnecessary thyroid nodule surgery

A portable biophotonics-enabled device could reduce invasive procedures in treating potentially cancerous thyroid nodules.

New acquisition has goal of developing laser-based cancer proton therapy system

HIL Applied Medical has acquired Nanolabz, which develops and fabricates smart targets for laser-based proton acceleration.

BLOGS

Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...

CONNECT WITH US

            

Twitter- BioOptics World

Copyright © 2007-2016. PennWell Corporation, Tulsa, OK. All Rights Reserved.PRIVACY POLICY | TERMS AND CONDITIONS