Laser optics + ultrasound imaging = potential noninvasive test for prostate cancer

Multispectral photoacoustic imaging, which combines laser optics and ultrasound imaging technologies, can reliably distinguish between benign and malignant prostate tissue, a new study indicates.

Related: Photoacoustic tomography is ready to revolutionize

Researchers at the University of Rochester (Rochester, NY) looked at 42 prostatectomy specimens using the new imaging technique. Multispectral photoacoustic imaging, still in its infancy, predicted 25 out of 26 benign tissues correctly and 13 out of 16 malignant tissues correctly, says Dr. Vikram Dogra, lead author of the study.

Lipids, water, oxyhemoglobin, and deoxyhemoglobin in the blood all respond to laser light, explains Dogra. "By observing increases and decreases in these four things, we can tell if the tissue is malignant or benign," he says. "Deoxyhemoglobin is the biggest distinguisher between malignant and benign. If deoxyhemoglobin increases even slightly in intensity, the odds that the tissue is malignant increases dramatically."

Transrectal ultrasound—the current gold standard to diagnose prostate cancer—has an overall success rate of about 70%, but it's invasive, says Dogra. His research team expects that the multispectral photoacoustic technique will be clinically available in about five years, he adds.

Dogra presented his study, which  at the American Roentgen Ray Society (ARRS) annual meeting on April 18, 2013, in Washington, DC. For more information, please visit http://www.urmc.rochester.edu/imaging/research/vikram-dogra/.

-----

Follow us on Twitter, 'like' us on Facebook, and join our group on LinkedIn

Subscribe now to BioOptics World magazine; it's free!

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

EUV spectral imaging tool can map cell composition in 3D

A newly developed spectral imaging instrument enables observation of how cells respond to new medications at a minute level.

Hydrogel bandage with embedded LEDs can deliver medicine to the skin

A newly developed hydrogel matrix can incorporate LEDs, other components, and tiny reservoirs and channels for drug delivery.

Preclinical studies demonstrate effectiveness of laser technologies for local pain control

Two laser methods can trigger on-demand release of a local anesthetic to provide repeatable, long-lasting pain management.

Multifunctional endoscope could treat, remove cancer cells in minimally invasive manner

A newly developed multifunctional endoscope could enable more targeted treatment for cancer patients.

AMD Lasers expands into hard-tissue dental laser market

Soft-tissue dental laser maker AMD Lasers has entered the hard-tissue dental laser market.

Leica Microsystems, NKT Photonics enter supercontinuum lasers agreement

Leica Microsystems and NKT Photonics have signed a supply contract to deliver significant numbers of NKT's supercontinuum lasers.

Ophthalmic optogenetics company raises $6M in funding

RetroSense Therapeutics has secured $6 million to further investigate the use of gene therapy and optogenetics to restore vision.

Two biomedical devices facilitated by light, optics receive NSBRI support

Two companies have been selected to receive grants for their biomedical devices enabled by light and optics.

Handheld NIR scanner could allow real-time 3D breast cancer screening

A newly developed handheld near-infrared (NIR) scanner has the potential to offer breast cancer imaging in real time.

BLOGS

Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...

CONNECT WITH US

            

Twitter- BioOptics World

Copyright © 2007-2015. PennWell Corporation, Tulsa, OK. All Rights Reserved.PRIVACY POLICY | TERMS AND CONDITIONS