PerkinElmer, Mass General team to develop next-gen sequencing system for cancer research

PerkinElmer (Waltham, MA) has entered into a collaboration with the Massachusetts General Hospital (MGH) Pathology Department and Cancer Center (Boston, MA) to develop a next-generation sequencing (NGS) informatics system for profiling genetic changes in tumors. Specifically, the system will be used in advanced cancer research.

Based on the company's Geospiza informatics platforms, the NGS system is expected to help guide development of cancer treatments by enabling genotype analysis to define key genetic targets from which clinically relevant information can be leveraged. Under the terms of the agreement, the company will develop a highly automated sample preparation and data analysis system suitable for cancer genotyping in clinical research at MGH. The Geospiza GeneSifter Laboratory and Analysis edition software platform will be enhanced with sophisticated variant detection algorithms, and the system will also integrate existing laboratory processes and equipment with enhanced laboratory information management systems (LIMS) and data analysis capabilities.

The informatics system will support the cancer research of Long Phi Le, MD, Ph.D., and A. John Iafrate, MD, Ph.D., who both serve as assistant pathologists at MGH's Pathology Department and Cancer Center.

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