Beckman Coulter cell sorter for multi-color flow cytometry

bowprodbeckman120210

The MoFlo Astrios next-generation cell sorter from Beckman Coulter (Brea, CA) features seven pinholes to spatially separate each of the seven lasers, enabling complex, multi-color sorting. Auto start-up defines when lasers and fluidics turn on, and a multi-fiber beam shaping optic creates flat-top beam profiles. Two stages control alignment for all seven lasers during sorter preparation.

-----

PRESS RELEASE

Next-Generation Cell Sorter from Beckman Coulter Enables Multi-Color Flow Cytometry Studies

MoFlo Astrios Features Bead-less Drop Delay Determination

Orange County, Calif. -- (December 1, 2010) -- MoFlo Astrios next-generation cell sorter from Beckman Coulter, Inc. leverages the stable fluidic design of the original MoFlo and the electronic processing of the MoFlo XDP, while expanding sorting capabilities with an array of laser options.  A range of unique software components further enhances instrument functionality.
 
Complex, multi-color sorting is enabled by seven pinholes that spatially separate each of the seven lasers.  Auto start-up allows the researcher to define when lasers and fluidics turn on, saving valuable time.  The multi-fiber Beam Shaping Optic creates flat-top beam profiles, providing short alignment times and high-level optic stability.  Two stages control the alignment for all seven lasers to simplify sorter preparation.

Beckman Coulter’s IntelliSort II is a bead-less drop delay determination and monitoring system.  Camera images and proprietary algorithms determine optimal drop delay without fluorescent beads being incorporated in the sample line. A quick-release nozzle design enables easy removal or swapping of the nozzle body and tip through the use of a single lever.

The auto-quality control allows system performance to be tracked and trended across 32 available parameters, while the updated Summit Software permits six-way sorting into tubes and sorting into plates having as many as 1536 wells.  Index-sorting logic tracks each plate-sorted cell back to its histogram or scatter plot.  A touchscreen control panel facilitates daily set-up with operations designed around core laboratory workflow.

“The range of features incorporated on MoFlo Astrios elevates the sorting and productivity capabilities available to the researcher,” said Brad Calvin, vice president and general manager of Beckman Coulter Flow Cytometry.  “This instrument reflects our commitment to providing scientists with instruments that combine cutting-edge performance with workflow gains.”

Biosafety features are prominent on the system.  The Aerosol Evacuation System (AES) filters particles from all chambers where aerosols have the potential of being generated.  A fully sealed sort-chamber housing on the redesigned R-Theta CyClone arm facilitates aerosol evacuation capabilities, which are tested to current ISAC guidelines.  A Custom BioSafety Level II option provides a cabinet tested to NSF-49 International Standards with the MoFlo Astrios inside.

-----

Posted by Lee Mather

Follow us on Twitter

Subscribe now to BioOptics World magazine; it's free!

Get All the BioOptics World News Delivered to Your Inbox

Subscribe to BioOptics World Magazine or email newsletter today at no cost and receive the latest news and information.

 Subscribe Now
Related Articles

Merz acquires laser tattoo removal device maker ON Light Sciences

Merz North America has acquired ON Light Sciences, which develops technologies to enhance laser-based dermatology procedures.

Shortwave-infrared device could improve ear infection diagnosis

An otoscope-like device that could improve ear infection diagnosis uses shortwave-infrared light instead of visible light.

Laser therapy extracts rare tumor that grew human hair, skin in boy's skull

About four years ago, a tumor comprised of human skin, hair, bone and cartilage was fast-growing inside a Ramsey, MN, 10-year-old youth's brain.

Low-level laser therapy could speed muscle recovery at Rio 2016 Olympics

The gold medal-winning women’s U.S. Gymnastics team is reportedly experimenting with infrared light therapy to alleviate pain and reduce swelling in its athletes. (Update: A spokesperson for ...
BLOGS

Neuro15 exhibitors meet exacting demands: Part 2

Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and p...

Why be free?

A successful career contributed to keeping OpticalRayTracer—an optical design software program—fr...

LASER Munich 2015 is bio-bent

LASER World of Photonics 2015 included the European Conferences on Biomedical Optics among its si...

White Papers

Understanding Optical Filters

Optical filters can be used to attenuate or enhance an image, transmit or reflect specific wavele...

How can I find the right digital camera for my microscopy application?

Nowadays, image processing is found in a wide range of optical microscopy applications. Examples ...

CONNECT WITH US

            

Twitter- BioOptics World